When you click the “Run Analysis” button, APSDS 5.0 uses APSDS32.exe to perform the numerical analysis.
This error is usually caused by APSDS32.exe not having the correct permissions to be executed by APSDS 5.0.
Check with your System Administrator that APSDS32.exe is not being blocked by your Firewall.
Try switching off your Firewall(s). Here are some links showing how to switch off Windows Firewall:
You may also be running a third-party firewall.